The total AUDPC of infection and disease severity, as well as the vascular discoloration rate of infected potato stems caused by noxa mutants (noxa-im-1, noxa-im-5, and noxa-im-7) were dramatically reduced on three sets of experiments conducted from 2016 to 2018 (Figure 4, Figure 5 and Figure 6). This evidence concerns the gene PMAIP1 and infection.