The G9a inhibitor BIX01294 triggers apoptosis and autophagy, increases apoptosis markers cleaved caspase 3, caspase 7, and poly (ADP-ribose) polymerase (PARP), and reduces H3K9 dimethylation (H3K9me2) in cultured GBM cells, in addition to promoting differentiation of GBM stem cells [42]. Here, CASP7 is linked to glioblastoma.