Therefore, malnutrition completely devastates optimum concentration of GH and IGF-1 in the serum, resulting in a lack of bone formation and growth performance; however, proper nutritional intervention can efficiently regulate GH and IGF-1 concentrations, leading to the promotion of bone formation and growth rate [14,15], which indicates that GH and IGF-1 are important nutritional markers. The gene discussed is IGF1; the disease is malnutrition.