In addition to hyposmia and RBD, they reported an association of striatal binding ratio with subtle motor dysfunction and PREDICT-PD risk estimates, which combine a number of risk and pre-diagnostic features of PD [193] Consistent with this report, elderly individuals with minimal parkinsonism without PD exhibited mild decrease in DAT availability in the striatum, which may be related to the disease process of prodromal PD [194]. The gene discussed is SLC6A3; the disease is Parkinson disease.