PTH and gonorrhea: Arnold et al. described a p15-q13 pericentromeric inversion in chromosome 11 in two non-related cases of benign PAs, which positioned the 5′-regulatory element of the PTH gene directly upstream to genes of the 11q13 locus, such as the CCDN1 proto-oncogene, inducing over-expression of cyclin D1 protein [37].