Menin, the protein encoded by the MEN1 gene, is an extremely pleiotropic tumor suppressor exerting various important anti-proliferative and anti-tumoral functions, such as regulation of gene expression, regulation of cell signaling, control of cell cycle progression, cell adhesion, cell mobility and apoptosis, maintenance of genome stability, and prevention/repair of DNA damage, via its direct interaction with numerous molecular partners [10]. This evidence concerns the gene MEN1 and neoplasm.