IL10 and preeclampsia: A recent meta-analysis of 56 studies on the circulating IL-10 levels in preeclamptic women revealed that the serum IL-10 levels were not significantly different before the onset of preeclampsia; however, once the clinical syndrome of preeclampsia occurs, IL-10 levels were significantly lower in preeclamptic women compared to normotensive controls (standardized mean differences, −0.79 [95% CI, −1.22 to −0.35]; p = 0.0004).