UCA1 and renal cell carcinoma: Transfection of shRNA, miRNA mimics or inhibitors in 786-O and Caki-1 kidney cell lines showed reciprocal interaction between lncRNA UCA1 and miR-182-5p, as well as their opposite effect on apoptosis and RCC progression, for example, the activating effect of UCA1 and the inhibitory effect of miR-182-5p on cell proliferation, migration, and tumorigenicity [36].