Indeed, previous studies have provided evidence for significant relationships with select microRNAs and regulated genes, such as let-7a/HMGA2, miRNA-125a-5p/STAT3, microRNA-98, and microRNA-328/ABCG2, to further elucidate potential mechanisms involved in ANRIL-mediated chemoresistance to cisplatin across different cancer types [31,32,33,34,35,36,52]. The gene discussed is HMGA2; the disease is cancer.