Previous studies have shown that ANRIL expression is upregulated in osteosarcoma tissues by comparison to adjacent normal tissues and may play a role in the regulation of cell proliferation, growth, and metastasis of osteosarcoma and other cancer types [30,31,32,43,44,45,46,47,48,49,50,51]. The gene discussed is CDKN2B-AS1; the disease is osteosarcoma.