On the other hand, 3-week post-injection of GCSF into AML- (AML + GCSF) and (AML + CYT)- (AML + CYT + GCSF), but not CYT- (CYT + GCSF) treated mice (which was similar to CYT group) significantly decreased the expression levels of IL-1 alpha and IL-1 beta in their testicular homogenates compare to AML-, and (AML + CYT)-treated, but not the CYT-treated, group, respectively (Figure 6D). This evidence concerns the gene CSF3 and acute myeloid leukemia.