In addition, 3-week post-injection of GCSF alone (GCSF) into the control group or into AML-treated mice (AML + GCSF), significantly increased expression levels of IL-10 but not IL-12A in cells of the testicular interstitial compartment were observed compared to control, but levels in AML + GCSF were similar to GCSF alone (Figure 7A,B, respectively). Here, IL12A is linked to acute myeloid leukemia.