In addition, the expression levels of IL-10 and IL-12 were similar in the CYT + AML group to those of CYT-treated mice; and post-injection of GCSF (CYT + AML + GCSF) did not significantly affect the expression levels of IL-10 and IL-12 compared to the CYT + AML group. Here, CSF3 is linked to acute myeloid leukemia.