However, post injection of GCSF into AML- (AML + GCSF)-, CYT- (CYT + GCSF) or (AML + CYT)- (AML + CYT + GCSF) treated mice significantly increased their testis weight 3 (except for AML + CYT group) and 5 weeks after the treatments compared to AML, CYT or AML + CYT groups (Figure 2B,C, respectively). The gene discussed is CSF3; the disease is acute myeloid leukemia.