On the other hand, post injection of GCSF into AML- (AML + GCSF), CYT- (CYT + GCSF), or (AML + CYT)- (AML + CYT + GCSF) treated mice showed improvement in the cell layers of the seminiferous tubules compared to the same groups without injection of GCSF (Figure 2D). This evidence concerns the gene CSF3 and acute myeloid leukemia.