On the other hand, 3-week post-injection of GCSF into AML (AML + GCSF), (CYT (CYT + GCSF) and AML + CYT (AML + CYT + GCSF) significantly increased sperm concentration (Figure 3B), motility (Figure 3C) and morphology (Figure 3D), but decreased spontaneous acrosome reaction (Figure 3E), increased fertility capacity (Figure 3F) and significantly increased the number of offspring (except in CYT + GCSF group) (Figure 3G) compared to AML-, (AML + CYT)- and CYT-treated groups. The gene discussed is CSF3; the disease is acute myeloid leukemia.