For example, while CHH is well established for being involved in metabolism regulation [19,20,21] and in particular in stress-induced hyperglycemia, it has also been shown to be active in repressing ecdysteroidogenesis in the Y-organ (i.e., MIH activity) and methyl farnesoate synthesis in the mandibular organ (i.e., MOIH activity) [11]. Here, RMRP is linked to Hyperglycemia.