After 4 weeks treatment with Ate, the mRNA and protein expression of PPARα and PPARγ increased significantly, and the dyslipidemia and liver lesions were improved to a certain extent, suggesting that PPARα/γ abnormal expression can lead to change in fat metabolism and result in the imbalance of both the lipid metabolism and lipid deposition in the liver. The gene discussed is PPARA; the disease is metabolic syndrome.