CXCR3 and peripheral nerve injury: In the present study, we showed that single intrathecal administration of the two highest doses of CXCR2 (NVP CXCR2 20) and CXCR3 ((±)-NBI 74330) antagonists to rats resulted in a strong, fast (observed already after one hour), and persistent analgesic effect for up to 6 h on day 7 after peripheral nerve injury, when neuropathic pain was fully developed.