IL6 and type 2 diabetes mellitus: In addition, research by Fu, Liu, Liu, Liu, Li, Wu and Liu [164] and Ramalho, et al. [168] suggest that SP might play an important in obesity and also for developing T2DM (type-2 diabetes mellitus) and asthma in obese patients, by increasing serum levels of IL-6, which is inextricably linked with tissue inflammation.