TLR2 and neoplasm: The combination of cetuximab treatment with Pam3CSK4-mediated TLR2 stimulation enhanced cytotoxicity, as well as cytokine production by NK cells, against both the ADCC-sensitive cell line VU-SCC-096 and the ADCC-insensitive cell line UM-SCC-47, although tumor cell killing and cytokine production remained lower in the latter.