We observed that PBMCs from both healthy donors (Figure 4A,C) and HNSCC patients (Figure 4B,C), that were co-cultured with VU-SCC-096 cells in the presence of cetuximab and Pam3CSK4, significantly increased the percentage of CD69+CD107a+ NK cells. Here, LAMP1 is linked to head and neck squamous cell carcinoma.