A plethora of potential anti-IL-6 therapeutics have been preclinically investigated; many available drugs could also be repurposed for application in cancer therapy (shortlisted in Supplementary Table S1; [25,146,154,155,165,169,170,173,174,228,229,230,231,232,233,234,235,236,237,238,239,240,241,242,243,244,245,246,247,248,249,250,251,252,253,254]). The gene discussed is IL6; the disease is cancer.