RORC and glioblastoma: Supplemental Figure S3 shows the correlations between expression of KRT37 (i.e., androgen expression) and the RORC-Treg gene basket, using the U133 dataset. Individual RORC-Treg markers are highly correlated with KRT37, all correlations p < 0.001, suggesting androgen-driven expansion and activation of Treg populations in GBM tumors [66]. In Figure 1D, we show pie charts representing the sex-steroid reporter levels and macrophage status using the U133 dataset. Using KRT37 androgen reportage, it is clear that there is a strong correlation between androgen reportage and RORC-Tregs.