After analyzing the TCGA database via the GEPIA2 webtool, we found that although a single gene of CD274 did not show any significant correlation to the overall survival among NSCLC patients, the two-gene signature of CD274 and SLC7A5 displayed a significantly positive correlation with shorter overall survival of NSCLC patients (Figure 6D). This evidence concerns the gene SLC7A5 and non-small cell lung carcinoma.