LAT and neoplasm: Using the GEPIA2 webtool to analyze an NSCLC dataset in the TCGA database, we also found that SLC7A5 mRNA was significantly negatively correlated with the gene signatures of Th1-like, effector T-cells, and resident memory T-cells (Figure S3); this lead to a hypothesis that LAT1 expression levels in NSCLC tumors may contribute to the immunosuppressive tumor microenvironment.