CD274 and non-small cell lung carcinoma: Due to the observations of the positive roles of LAT1 or PD-L1 expression in CSC activity in NSCLC cells, we next used the parental A549 or H1299 cells, rather than the pemetrexed-resistant A400 cells, to understand the general impact of the expression patterns of cell surface LAT1/PD-L1 on the CSC activity of NSCLC cells.