ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: Previously, we performed in vitro and in silico studies for the benzyl esters of asiatic acid (1), betulinic acid (2), glycyrrhetinic acid (3), hederagenin (4), oleanolic acid (5), ursolic acid (6), and gypsogenin (7), and the substituted benzyl esters of gypsogenin (8, 9) (Figure 1) to identify anti-chronic myelogenous leukemia (CML) agents targeting ABL1 kinase [37].