Altered energy metabolism in cancer cells is accompanied by the upregulation of several glycolytic enzymes, such as GLUT1, hexokinase 2, phosphofructokinase, enolase 1 (ENO1), aldolase A (ALDOA), lactate dehydrogenase A, and pyruvate dehydrogenase kinase, which stimulate the Warburg effect [4]. This evidence concerns the gene ENO1 and cancer.