Substantial factors to consider in this decision-making are the age and health condition of the patient; genetic factors, tumor characteristics such as the origin, localization, size, and immunohistochemical proliferation marker Ki67; and tumor uptake in molecular imaging such as SSTR-positron emission tomography (PET) and [18F]F-Fluorodeoxyglucose (FDG). The gene discussed is MKI67; the disease is neoplasm.