Further, in beta cells of pancreatic islets of the type-1 diabetic mice (T1DM), resveratrol upregulated CXC chemokine ligand 16 (CXCL16) expression, which works as a scavenger receptor for ox-LDL accompanied with reduction of ox-LDL expression and inhibition of coagulation cascade by downregulating tissue factor (TF). The gene discussed is CXCL16; the disease is type 1 diabetes mellitus.