FASN and pancreatic neoplasm: Previous studies have revealed that GA inhibits de novo lipogenesis in pancreatic cancer (Panc-1), BxPC-3, and hepatocellular carcinoma (HepG2) cell lines by inducing the activation of 5′-adenosine monophosphate-activated protein kinase (AMPK) signaling and downregulating the expression of acetyl-CoA carboxylase (ACC) and fatty acid synthase (FASN) [11].