MPO and keratitis: Zhao et al. [34] investigated the effect of fenretinide in Aspergillus fumigatus keratitis In vivo in a mouse model as well as In vitro in a THP-1-derived macrophage cell line infected with A. fumigatus. In both experimental models, the pretreatment with fenretinide contributed to protecting corneal transparency during A. fumigatus keratitis in the early phase of the infection by reducing neutrophil recruitment, decreasing myeloperoxidase (MPO) levels and increasing apoptosis.