CASP3 and cancer: Resveratrol causes a high production of nitric oxide synthases (NOS), thus inhibiting cell proliferation [120], inducing apoptosis (through the intrinsic pathway via the activation of caspase 3 and caspase 9, the determined release of cytochrome c, upregulation of Bax expression, and downregulation of Bcl-2 expression [119]) promoting antitumor immune responses, and preventing cancer cell adhesion, migration (also reduced by resveratrol through the EGFR/PI3K signaling pathway [121]), and invasion by modulating active molecules and gene expression through various signaling pathways (Figure 8).