ACE and Thromboembolism: Since the risk of thromboembolism is high, especially in patients with severe COVID-19 pneumonia, and decisive involvement of the balance between ACE1 and ACE2 activities is suggested in the thrombo-inflammatory process, 68 patients with severe COVID-19 pneumonia were divided according to the development of pulmonary embolism (PE) (25 PE + patients, 43 PE- patients).