Familial Hyperinsulinemic Hypoglycemia has been correlated with pathogenic variants in 15 genes: ABCC8, KCNJ11, GCK, GLUD-1, HADH1, SLC16A1, HNF4A, HNF1A, UCP2, PMM2, CACNA1D, HK1, PGM1, FOXA2 and EIF2S3. This evidence concerns the gene GCK and hyperinsulinemic hypoglycemia.