The comparison between the list of DEGs from the GO analysis and the list of DEGs obtained by the Venn diagram revealed five genes (IL31RA, ACOD1, OSCAR, MT1M, TBX3) downregulated in L444P/N GBA carriers compared to L444P/N GBA-PD and controls, and one downregulated gene (DUSP1) in L444P/N GBA-PD patients compared to L444P/N GBA carriers and controls (Figure 3A), and one upregulated gene (KIAA0319) in L444P/N GBA-PD patients and L444P/N GBA carriers compared to controls (Figure 3B). This evidence concerns the gene DUSP1 and Parkinson disease.