PRPF31 and nasopharyngeal carcinoma: These results are consistent with the modest increases in PRPF31 expression previously reported in NPC LCLs compared with LCLs from affected RP11 patients [18] and suggest that the inheritance of the 4-copy MSR1 repeat element is associated with increased PRPF31 expression in NPC fibroblasts, compared with an age-matched RP11 patient carrying homozygous 3-copy repeats.