In addition, the patients with younger ages (Figure S9Q–R); negative EBV (Figure S9S–T); upregulated MLH1 (Figure S9U–V); and advanced clinicopathologic traits (e.g., perineural invasion, lymphovascular invasion, venous invasion, positive lymph nodes located at the body/whole, and signet ring cell carcinoma) (Figures S9W–AB and S10A–E) were correlated with the low-PS group, whereas a high-PS group was related to better clinicopathological outcomes. This evidence concerns the gene MLH1 and signet ring cell carcinoma.