CD8A and neoplasm: A further analysis indicated that pyroptosis cluster A exhibited the lowest tumor purity, the highest immune score, and abundant antitumor lymphocyte cell subpopulations (e.g., activated B cells, activated CD4+ T cells, and activated CD8+ T cells); pyroptosis cluster B retained the highest tumor purity and the lowest immune/stromal scores and immune cells; and like pyroptosis cluster A, pyroptosis cluster C exhibited the highest stromal score along with the immune cells (Figure 3C–E and Figure S4D).