CD276 is present at low levels in normal tissues but is overexpressed by bladder, breast, cervical, colorectal, esophageal, glioma, kidney, liver, lung, ovarian, pancreatic, prostate, liver, oral squamous cell carcinoma, endometrial cancer, squamous cell carcinoma, and gastric cancer cells [29,30,31,32,33,34,35,36,37,38,39]. The gene discussed is CD276; the disease is oral cavity squamous cell carcinoma.