TFF2 and obesity due to melanocortin 4 receptor deficiency: The study has shown that the Tff2 KO mice, compared to the wild-type (WT) mice, are in fact protected from HFD-induced obesity with an increased lipids excretion as well [24] which correlates with the exacerbation of weight loss by TFF2 deficiency shown by Judd et al. [25].