The TIM3, PD1 and CTLA-4 expressions on CD4+ and CD8+ in lymphocytes and total monocytes were all significantly higher in the LTBI-non-CKD group than in the HC group, except for the percentage of CTLA-4 expression on monocytes (CTLA-4+monocyte) with a marginally significantly lower value (6.6 ± 5.3 vs. 11.8 ± 10.0, p = 0.065). The gene discussed is HAVCR2; the disease is chronic kidney disease.