Recently, it has been concluded that ω-3 FAs have an anti-inflammatory effect, through the modification of TLR4 signaling pathway activation, by suppressing dimerization in cellular membranes, leading to the inhibition of TLR4 expression and further mitigation of meta-inflammation, cardiovascular disease, and risks of diabetes myelitis 2 in obese humans [11,12]. Here, TLR4 is linked to cardiovascular disorder.