Regarding overall survival (OS), we found that FABP4 (Cox p = 0.027956, hazard ratio (HR) (95% confidence interval (CI)) = 1.25 (1.02–1.54)) and FABP6 (Cox p = 0.009886, HR (95% CI) = 1.51 (1.10–2.07)) were significantly correlated with the prognosis of CRC patients. The gene discussed is FABP6; the disease is colorectal carcinoma.