The use of probiotic (L. reuteri) in the group of pregnant women and infants was evaluated by Abrahamsson et al. Despite the cumulative incidence of AD was similar in the L. reuteri and the placebo groups (36% vs. 34%), IgE-associated eczema was less common in the L. reuteri group, although the difference was only statistically significant during the second year of life (8% vs. 20%) [27]. This evidence concerns the gene IGHE and Alzheimer disease.