DSG3 and pemphigus: In this study, we showed that (i) modifications of the N-glycan structure of patients’ IgG or the AK23 anti-DSG3 mAb modified its in vitro pathogenicity; (ii) IgG N-glycans profiles seemed to be relatively stable during the course of pemphigus, and did not seem to be correlated with the in vitro pathogenic effects.