DSG1 and pemphigus: Overall, these results showed a strong correlation between clinical activity, serum anti-DSG3 antibodies titers, and demonstration of the in vitro pathogenic activity of serum IgG at the onset of pemphigus, while the achievement of clinical remission under treatment, at month 6, was also strongly correlated with a drop in anti-DSG antibodies, and a loss of the pathogenic activity of patients’ IgG.