Within the NF-kB signalling pathway in hepatocellular carcinoma, tumor necrosis factor, alpha induced protein 1 (TNFAIP1) was shown to interact with CK2β, promoting its ubiquitination and degradation, suppressing CK2β-dependent NF-kB activation [81]. The gene discussed is NFKB1; the disease is hepatocellular carcinoma.