The results show that the expression levels of the top 10 upregulated CRC-associated gene transcripts (DPEP1, KRT80, FABP6, NKD2, FOXQ1, CEMIP, ETV4, TESC, FUT1, and GAS2) relate with CRC prognosis, and six of the genes (KRT80, FABP6, NKD2, FOXQ1, ETV4, and GAS2) are highly expressed in the CRC patients in advanced stages. This evidence concerns the gene NKD2 and colorectal carcinoma.