VEGFA and neoplasm: There are shared characteristics between tumor endothelial cells and human umbilical vein endothelial cells (HUVECs) cultured with MAPF, including increased mitosis, filopodia formation, and aberrant angiogenesis [12,13]; the cancerous cells stimulate endothelial cells to increase EGFR expression through VEGF-related paracrine effects [14]; the cancerous cells stimulate endothelial cells to increase EGFR expression through VEGF-related paracrine effects [15].