CASP1 and chronic kidney disease: To determine the effects of CKD on the inflammasome regulation in kidney tissue, protein levels of NLRP3, and inflammasome-related proteins pro-caspase-1 (p45), caspase-1 (p20), and pro-IL-1β were measured together with superoxide dismutase-1 (SOD-1) as an additional marker of oxidative stress.