Among the enriched genes in IDHMUT and IDH1WT+2HG AML cells associated with these two small molecules, we identified common genes related to monocytic and granulocytic differentiation (RXRα, ITGAM or CD11b, ITGAX or CD11c, CEBPε) (Figure 1B and Table S3). Here, RXRA is linked to acute myeloid leukemia.