TNF and neoplasm: Similarly, the authors show that ALCAM transcript levels in tumours are positively correlated with a number of inflammatory markers, including TNFα (tumour necrosis factor alpha), IL4 (interleukin 4), and NF-κB, and that Her2-positive and high-grade tumours had high ALCAM proteins and Luminal-A tumours had the strongest ALCAM staining [58].