Although it has been shown that, in a relatively small cohort of PNET (pancreatic neuroendocrine tumours), raised tissue levels of ALCAM are positive factors for both recurrence-free survival and disease-specific survival [97,98], the same authors, in a larger pancreatic cancer cohort (n = 264) did not find a connection between tissue ALCAM and the survivals [62]. Here, ALCAM is linked to familial pancreatic carcinoma.