Finally, based on our observation that the expression of a specific microRNA defines chemoresistance in EOC through modulation of angiogenic factor, we also evaluated the expression and prognostic significance of miR-484 that, in ovarian cancer, modulate the expression of both VEGFB in cancer cells and, upon secretion, of VEGFR2 in endothelial cells [20]. This evidence concerns the gene VEGFB and ovarian cancer.