The densities of tumor-infiltrating CD8 T, CD8 TRM, CD39+ CD8 TRM, and PD-L1+ CD8 TRM cells are shown by the best response in Figure 3A. Objective responses were associated with higher densities of tumor-infiltrating CD39+ CD8 TRM cells (p = 0.04 for both CR/PR vs. stable disease and CR/PR vs. progressive disease comparisons). This evidence concerns the gene CD274 and neoplasm.