ZEB1 and cancer: For instance, ZEB1/2, SNAI1/2, TWIST, and GSC (Goosecoid) are EMT-TFs that are often activated by signaling pathways, such as TGFβ, and can drive varying extents of EMT in cancer cells through repressing various epithelial genes (such as E-cadherin) and/or inducing the expression of mesenchymal genes (such as vimentin) [8,9,10,11,12,13].