The SFK comprises 12 members, (Src, Fyn, Yes, Yrk, Lyn, Hck, Fgr, Blk, Lck, Brk, Srm, and Frk) three of which, Src, Fyn, and Yes, are expressed prominently in many cell types, including human pancreatic cancer cell lines [54], while other members have a more restricted expression pattern, especially to cells of hematopoietic origin [55]. The gene discussed is YES1; the disease is familial pancreatic carcinoma.