The dysfunction of the SDH complex is linked to several diseases, varying from severe neuromuscular disorders [1] to different types of cancer including phaeochromocytomas and paragangliomas (PPGLs), gastrointestinal stromal tumour, renal cell carcinoma (RCC), pituitary adenoma, and pancreatic neuroendocrine tumours [2,3]. This evidence concerns the gene SDHB and pheochromocytoma.