In both cases, these syndromes should be tackled with liposomal formulation (in olive pomace oil) of the flavone luteolin (e.g., PureLut® or FibroProtek®) along with the antihistamine rupatadine, which also exhibit an anti-platelet activating factor (PAF) activity and inhibit mast cells that have been involved in the pathogenesis of cytokine storms in COVID-19 [40]. The gene discussed is PCLAF; the disease is COVID-19.