Additionally, expression of cytokines such as CXCL12, CSF-1, IL-17B, CCL2, S100A3, S100A4, IL-33 and IL-34, which are known to recruit tumor-associated macrophages (TAMs), was dominant in double-positive cells (Figure 2D and Figure S7). The gene discussed is CXCL12; the disease is neoplasm.