RNA-seq data also demonstrated that several genes related to adoptive immune systems which have pro-tumor action, such as TGFβ2, TGFBI, TGFBR1, TGFBR3, PLAU, IL-1β, and IL-33 are higher in Pn-positive cells than Pn-negative cells. Here, TGFBR1 is linked to neoplasm.