Other tumor types harboring an NRG1 fusion included PDAC, CRC, gastrointestinal stromal tumors (GISTs), squamous cell carcinomas (SCCs), breast, cholangiocarcinoma, thyroid, renal cell carcinoma, bladder, ovarian, neuroendocrine and sarcoma and are clinically actionable oncogenic drivers [17,18,19,20,21]. The gene discussed is NRG1; the disease is neoplasm.